Image Research Challenge: Health DCU Life Sciences Institute Research Challenge: Health Area of Research Excellence: Cancer Currently Funded Projects: Profile ADCs and Immune Modulation - Understanding and Managing Immune-Related Side Effects of Anti-Cancer Treatments Model OvaLoad: Enhanced targeted DNA damage in ovarian cancer Developing new targeted treatment strategies for triple negative breast cancer Investigating new therapeutic modalities for a rare childhood cancer Immune responses to intratumoural bacteria in cancer Target Rational therapeutic combinations with DXd-based ADCs Investigating the combination of tyrosine kinase inhibitors and antibody-drug conjugates in HER2+ cancers Translate Breast cancer biomarkers and novel treatment strategies Characterising the immune response to antibody-based therapies in cancer