Damien King

Dr.

Contact Details


S3155
T:Ext. 6277

E:damien.king@dcu.ie

Assistant Professor
X221
School of Biotechnology, Lonsdale Building
Dublin City University
D09 K20V
T:+353 1 700 5394

E:damien.king@dcu.ie
W:https://www.linkedin.com/in/damien-king-3a180440/
Profile Photo

Dr. Damien King is an Assistant Professor in the School of Biotechnology since September 2022 focusing on modules in the field of Bioprocess Engineering. 

He completed a BEng degree in Electronic Engineering (2001) and a PhD (2005) in the Electronic and Computer Engineering (ECE) Department at the University of Limerick (UL).  His PhD thesis focused on the application of Artificial Neural Network pattern recognition techniques to developed optical fibre sensor systems deployed for environmental monitoring applications. Upon completion of his PhD he undertook a postdoctoral role in the optical fibre research centre in the ECE department (2006).

In 2006 he took up a role as postdoctoral researcher with the Stokes Institute in UL working on a Enterprise Ireland Commercialization Fund project developing optical fibre sensor systems for strain monitoring applications on buildings and structures. Upon completion of his postdoctoral role in 2008, he joined Stokes Bio Ltd. - a spin out company from UL. The company was acquired by Life Technologies in 2010 and he worked within the R&D group as a Senior Systems Engineer. 

In 2012 he joined the Microfluidics Platforms Research Group in School of Physics, DCU and worked as a Research Fellow in the development of microfluidic systems for single cell analysis applications (cardiovascular disease, cancer assays, cell line development).

This work fed into the establishment of the Fraunhofer Project Centre for Embedded Bioanalytical Systems at DCU (FPC@DCU) in 2017 where he worked as group lead in the Cell Handling Applications Group within the centre.

Book Chapter

Year Publication
2016 Glynn, M;King, D;Ducree, J (2016) 'Systems Biology in Single Cells' In: ESSENTIALS OF SINGLE-CELL ANALYSIS: CONCEPTS, APPLICATIONS AND FUTURE PROSPECTS. BERLIN : SPRINGER-VERLAG BERLIN. [DOI]
2014 Damien King;Jens Ducree (2014) 'Optical Detection on Centrifugal Microfluidic Lab-on-a-disc Platforms' In: Encyclopedia of Microfluidics and Nanofluidics. UK : Springer Link. [Link] https://link.springer.com/referenceworkentry/10.1007/978-3-642-27758-0_1785-1

Peer Reviewed Journal

Year Publication
2021 Henderson BD;Kinahan DJ;Rio J;Mishra R;King D;Torres-Delgado SM;Mager D;Korvink JG;Ducrée J; (2021) 'Siphon-Controlled Automation on a Lab-on-a-Disc Using Event-Triggered Dissolvable Film Valves'. Biosensors, 11 (3). [DOI]
2021 Molony, C. and King, D. and Di Luca, M. and Kitching, M. and Olayinka, A. and Hakimjavadi, R. and Julius, L.A.N. and Fitzpatrick, E. and Gusti, Y. and Burtenshaw, D. and Healy, K. and Finlay, E.K. and Kernan, D. and Llobera, A. and Liu, W. and Morrow, D. and Redmond, E.M. and Ducrée, J. and Cahill, P.A. (2021) 'Disease-Relevant Single Cell Photonic Signatures Identify S100β Stem Cells and their Myogenic Progeny in Vascular Lesions'. . [Link] [DOI]
2019 King D.;Glynn M.;Cindric S.;Kernan D.;O’Connell T.;Hakimjavadi R.;Kearney S.;Ackermann T.;Berbel X.;Llobera A.;Simonsen U.;Laursen B.;Redmond E.;Cahill P.;Ducrée J. (2019) 'Label-Free Multi Parameter Optical Interrogation of Endothelial Activation in Single Cells using a Lab on a Disc Platform'. Scientific Reports, 9 (1). [DOI]
2019 Costello A.;Lao N.;Gallagher C.;Capella Roca B.;Julius L.;Suda S.;Ducrée J.;King D.;Wagner R.;Barron N.;Clynes M. (2019) 'Leaky Expression of the TET-On System Hinders Control of Endogenous miRNA Abundance'. Biotechnology journal, 14 (3). [DOI]
2014 Damien King;Mary O'Sullivan;Jens Ducree (2014) 'Optical Detection Strategies for Centrifugal Microfluidic Platforms'. Journal of Modern Optics, . https://doi.org/10.1080/09500340.2013.873496
2014 O'Connell TM, King D, Dixit C, O'Connor B, Walls D and Ducree J (2014) 'Sequential glycan profiling at single cell level with the microfluidic lab-in-a-trench platform: a new era in experimental cell biology'. Lab on a Chip, DOI: 10.1039/C4LC00618F .
2007 Elfed Lewis;Cormac Sheridan;Marion O'Farrell;Damien King;Colin Flanagan;William B Lyons;Colin Fitzpatrick (2007) 'Principal Component Analysis and Artificial Neural Network Based Approach to Analysing Optical Fibre Sensors Signals'. Sensors and Actuators, A: Physical, . https://doi.org/10.1016/j.sna.2007.02.012
2006 Damien King;William B Lyons;Colin Flanagan;Elfed Lewis (2006) 'Utilisation of Pattern Recognition Techniques to Interpret Complex Data from a Multipoint Optical Fibre Ethanol Concentration Sensor System'. Sensors and Actuators, A: Physical, . https://doi.org/10.1016/j.sna.2006.10.035
2004 Damien King;William B Lyons;Colin Flanagan;Elfed Lewis (2004) 'Interpreting Complex Data From a Three-Sensor Multipoint Optical Fibre Ethanol Concentration Sensor System Using Artificial Neural Network Pattern Recognition'. MEASUREMENT SCIENCE & TECHNOLOGY, . [DOI]
2004 Damien King;William B Lyons;Colin Flanagan;Elfed Lewis (2004) 'A Multipoint Optical Fibre Sensor System For Use In Process Water Systems Based on Artificial Neural Network Techniques'. Sensors and Actuators, A: Physical, . https://doi.org/10.1016/j.sna.2004.03.068
2004 Damien King;William B Lyons;Colin Flanagan;Elfed Lewis (2004) 'An Optical-Fiber Sensor for Use in Water Systems Utilizing Digital Signal Processing Techniques and Artificial Neural Network Pattern Recognition'. IEEE Sensors Journal, . [DOI]
2003 Damien King;William B Lyons;Colin Flanagan;Elfed Lewis (2003) 'An Optical Fibre Ethanol Concentration Sensor Utilizing Fourier Transform Signal Processing Analysis and Artificial Neural Network Pattern Recognition'. Journal of Optics A: Pure and Applied Optics, . [DOI]
Certain data included herein are derived from the © Web of Science (2023) of Clarivate. All rights reserved.

Honors and Awards

Date Title Awarding Body
01/06/2018 DCU Professional Skills for Research Leaders Programme Institute of Leadership & Management (ILM) - The City and Guilds of London Institute
01/12/2022 DCU Invent Commercialization Award DCU Invent

Employment

Employer Position From / To
FPC@DCU Principal Investigator - Cell Handling Group 01/01/2017 - 31/03/2023
Stokes Bio - a part of Life Technologies Senior Systems Engineer - R&D 01/12/2008 - 31/12/2011
ECE Department, UL Assistant Lecturer (Part Time) 01/01/2003 - 31/12/2006
ECE Department, UL Postdoctoral Researcher 01/12/2005 - 30/11/2006
Stokes Institute, UL Postdoctoral Researcher 01/12/2006 - 30/11/2008
Stokes Institute, UL Research Fellow 01/02/2012 - 30/06/2012
DCU Research Fellow - Microfluidics Platforms Research Group 01/11/2012 - 31/12/2016
Tellabs R&D Engineer - Hardware (College Placement) 01/06/1999 - 29/02/2000

Education

Start date Institution Qualification Subject
01/10/1997 University of Limerick BEng Electronic Engineering
01/10/2001 University of Limerick PhD Optical Fibre Sensors and Artificial Neural Network Pattern Recognition

Other Activities

Description

Patents

Patent Number Title Inventor Granted
20140127701 End-Point Optical System and Method of Use Stokes Bio Ltd 08/05/2014
10513729 Biological detection system and method of use Stokes Bio Ltd 24/12/2019

Enterprise Engagement

Year Engagement Type Client Description
2023 Other BioPhorum Innovation Hub Member

Research Interests

Microfluidic Based Single Cell Analysis

Microfluidic Cell Enrichment Techniques

Process Analytical Technology for Upstream Processing in Biopharmaceutical Production and Bioprocessing 

Cell Line Development

Organoids in Cancer 

Extracellular Vesicles as diagnostics and therapeutics

Biophotonic devices

Research Projects

Title Role Description Start date End date
Implementing a vector-free cell transfection protocol in a microfluidic chip DCU PI 11/06/2018 10/03/2019
A microfluidic system for personalized cancer therapy based on organoid models DCU PI 28/10/2019 20/12/2019
uPAT – Microfluidic Process Analysis Technology for Streamlined Upstream Bioprocess Monitoring DCU PI 01/08/2017 31/07/2019
Cell Enrichment Module Mallinckrodt & DCU will conduct research services in connection with the Cell Enrichment Module. The project is concerned with the automation and streamlining of workflows associated with the development of cell therapies. DCU PI 09/12/2019 08/12/2020
Development of Extracellular Vesicles loaded hydrogel coatings with immunomodulatory activity for Promoted Regenerative Osseointegration of revision endoprosthesis DCU PI 01/01/2019 31/12/2022

Current Postgraduate Students

Student Name Degree Supervision
Pedersen ,Tom Erik PhD-track Supervisor
Palanga ,Letizia PhD-track Supervisor

Teaching Interests

Bioprocess Engineering, Upstream Processing, Downstream Processing, Modelling, Simulation, Data Analysis, Process Analytical Technologies, Bio-photonics, Lab on a Chip Systems, Sensors and Actuators 

Modules Coordinated

Term Title Subject
2023 BE214
2023 BE371
2023 BE215