Dr. Tanya Levingstone was awarded a bachelors degree in Biomedical Engineering from Dublin City University in 2003. She then undertook her PhD in the area of bioceramic coatings in the School of Mechanical and Manufacturing Engineering and the National Centre for Plasma Science and Technology (NCPST) in DCU. In 2008, she joined the Tissue Engineering Research Group in the Royal College of Surgeons in Ireland, where she led the cartilage tissue engineering faction of the group. Dr. Levingstone returned to DCU to join the academic staff in the School of Mechanical and Manufacturing Engineering in 2016 where she leads a translational research group focused on the development of novel biomaterials based approaches for bone and cartilage repair.
Book
Peer Reviewed Journal
Year | Publication | |
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2022 | Levingstone, T.J.;Sheehy, E.J.;Moran, C.J.;Cunniffe, G.M.;Diaz Payno, P.J.;Brady, R.T.;Almeida, H.V.;Carroll, S.F.;O'Byrne, J.M.;Kelly, D.J.;Brama, P.A.;O’ Brien, F.J. (2022) 'Evaluation of a co-culture of rapidly isolated chondrocytes and stem cells seeded on tri-layered collagen-based scaffolds in a caprine osteochondral defect model'. Biomaterials and Biosystems, 8 . [Link] [DOI] | |
2022 | Redmond, J;McCarthy, HO;Buchanan, P;Levingstone, TJ;Dunne, NJ (2022) 'Development and characterisation of 3D collagen-gelatin based scaffolds for breast cancer research'. Biomaterials advances, 142 . [DOI] | |
2022 | Al-Kharusi, G;Dunne, NJ;Little, S;Levingstone, TJ (2022) 'The Role of Machine Learning and Design of Experiments in the Advancement of Biomaterial and Tissue Engineering Research'. Bioengineering (Basel, Switzerland), 9 (10). [DOI] | |
2022 | Tzagiollari, A;McCarthy, HO;Levingstone, TJ;Dunne, NJ (2022) 'Biodegradable and Biocompatible Adhesives for the Effective Stabilisation, Repair and Regeneration of Bone'. Bioengineering (Basel, Switzerland), 9 (6). [DOI] | |
2022 | Sahebalzamani, M;Ziminska, M;McCarthy, HO;Levingstone, TJ;Dunne, NJ;Hamilton, AR (2022) 'Advancing bone tissue engineering one layer at a time: a layer-by-layer assembly approach to 3D bone scaffold materials'. Biomaterials Science, . [DOI] | |
2021 | Redmond J;McCarthy H;Buchanan P;Levingstone TJ;Dunne NJ; (2021) 'Advances in biofabrication techniques for collagen-based 3D in vitro culture models for breast cancer research'. Materials Science and Engineering C, 122 . [DOI] | |
2021 | Levingstone T;Ali B;Kearney C;Dunne N; (2021) 'Hydroxyapatite sonosensitization of ultrasound-triggered, thermally responsive hydrogels: An on-demand delivery system for bone repair applications'. Journal of Biomedical Materials Research - Part B Applied Biomaterials, . [DOI] | |
2021 | Levingstone, T.J.;Moran, C.;Almeida, H.V.;Kelly, D.J.;O'Brien, F.J. (2021) 'Layer-specific stem cell differentiation in tri-layered tissue engineering biomaterials: Towards development of a single-stage cell-based approach for osteochondral defect repair'. Materials Today Bio, 12 . [Link] [DOI] | |
2021 | McGivern, S;Boutouil, H;Al-Kharusi, G;Little, S;Dunne, NJ;Levingstone, TJ (2021) 'Translational Application of 3D Bioprinting for Cartilage Tissue Engineering'. Bioengineering (Basel, Switzerland), 8 (10). [DOI] | |
2020 | Levingstone TJ;Herbaj S;Redmond J;McCarthy HO;Dunne NJ; (2020) 'Calcium Phosphate Nanoparticles-Based Systems for RNAi Delivery: Applications in Bone Tissue Regeneration'. Journal of Nanomaterials, 10 (1). [DOI] | |
2019 | Levingstone TJ;Herbaj S;Dunne NJ; (2019) 'Calcium Phosphate Nanoparticles for Therapeutic Applications in Bone Regeneration'. Journal of Nanomaterials, 9 (11). [DOI] | |
2019 | De Guzman K.;Al-Kharusi G.;Levingstone T.;Morrin A. (2019) 'Robust epidermal tattoo electrode platform for skin physiology monitoring'. Analytical Methods, 11 (11):1460-1468. [DOI] | |
2019 | Cunniffe GM;Díaz-Payno PJ;Sheehy EJ;Critchley SE;Almeida HV;Pitacco P;Carroll SF;Mahon OR;Dunne A;Levingstone TJ;Moran CJ;Brady RT;O'Brien FJ;Brama PAJ;Kelly DJ; (2019) 'Tissue-specific extracellular matrix scaffolds for the regeneration of spatially complex musculoskeletal tissues'. Biomaterials, 188 . [DOI] | |
2017 | Levingstone, TJ;Barron, N;Ardhaoui, M;Benyounis, K;Looney, L;Stokes, J (2017) 'Application of response surface methodology in the design of functionally graded plasma sprayed hydroxyapatite coatings'. Surface and Coatings Technology, 313 :307-318. [DOI] | |
2017 | Brougham, CM;Levingstone, TJ;Shen, NA;Cooney, GM;Jockenhoevel, S;Flanagan, TC;O'Brien, FJ (2017) 'Freeze-Drying as a Novel Biofabrication Method for Achieving a Controlled Microarchitecture within Large, Complex Natural Biomaterial Scaffolds'. Advanced healthcare materials, 6 . [DOI] | |
2016 | Conor J Moran, Ashwanth Ramesh, Pieter AJ Brama, John M O’Byrne, Fergal J O’Brien, Tanya J Levingstone (2016) 'The benefits and limitations of animal models for translational research in cartilage repair'. 3 (1):1-12. [Link] [DOI] | |
2016 | Stack, J.D., Levingstone, T.J., Lalor, W., Sanders, R., Kearney, C., O'Brien, F.J., David, F. (2016) 'Repair of large osteochondritis dissecans lesions using a novel multilayered tissue engineered construct in an equine athlete'. . [Link] [DOI] | |
2016 | Levingstone, TJ;Thompson, E;Matsiko, A;Schepens, A;Gleeson, JP;O'Brien, FJ (2016) 'Multi-layered collagen-based scaffolds for osteochondral defect repair in rabbits'. Acta Biomaterialia, 32 :149-160. [DOI] | |
2016 | Levingstone T.;Ramesh A.;Brady R.;Brama P.;Kearney C.;Gleeson J.;O'Brien F. (2016) 'Cell-free multi-layered collagen-based scaffolds demonstrate layer specific regeneration of functional osteochondral tissue in caprine joints'. Biomaterials, 87 :69-81. [DOI] | |
2015 | Brougham, C.M., Levingstone, T.J., Jockenhoevel, S., Flanagan, T.C., O'Brien, F.J. (2015) 'Incorporation of fibrin into a collagen-glycosaminoglycan matrix results in a scaffold with improved mechanical properties and enhanced capacity to resist cell-mediated contraction'. 26 :205-214. [Link] [DOI] | |
2015 | Matsiko, A., Levingstone, T.J., Gleeson, J.P., O'Brien, F.J. (2015) 'Incorporation of TGF-Beta 3 within Collagen-Hyaluronic Acid Scaffolds Improves their Chondrogenic Potential'. 4 (8):1175-1179. [Link] [DOI] | |
2015 | Chikarakara E.;Fitzpatrick P.;Moore E.;Levingstone T.;Grehan L.;Higginbotham C.;Vázquez M.;Bagga K.;Naher S.;Brabazon D. (2015) 'In vitro fibroblast and pre-osteoblastic cellular responses on laser surface modified Ti-6Al-4V'. Biomedical Materials, 10 (1). [DOI] | |
2015 | David F.;Levingstone T.;Schneeweiss W.;de Swarte M.;Jahns H.;Gleeson J.;O'Brien F. (2015) 'Enhanced bone healing using collagen-hydroxyapatite scaffold implantation in the treatment of a large multiloculated mandibular aneurysmal bone cyst in a thoroughbred filly'. Journal of tissue engineering and regenerative medicine, 9 (10):1193-1199. [DOI] | |
2015 | Levingstone T.;Ardhaoui M.;Benyounis K.;Looney L.;Stokes J. (2015) 'Plasma sprayed hydroxyapatite coatings: Understanding process relationships using design of experiment analysis'. Surface and Coatings Technology, 283 :29-36. [DOI] | |
2014 | Levingstone, T.J., Matsiko, A., Dickson, G.R., O'Brien, F.J., Gleeson, J.P. (2014) 'A biomimetic multi-layered collagen-based scaffold for osteochondral repair'. 10 (5):1996-2004. [Link] [DOI] | |
2013 | Matsiko, A., Levingstone, T.J., O'Brien, F.J. (2013) 'Advanced strategies for articular cartilage defect repair'. 6 (2):637-668. [Link] [DOI] | |
2012 | Matsiko, A., Levingstone, T.J., O'Brien, F.J., Gleeson, J.P. (2012) 'Addition of hyaluronic acid improves cellular infiltration and promotes early-stage chondrogenesis in a collagen-based scaffold for cartilage tissue engineering'. 11 :41-52. [Link] [DOI] | |
2010 | Cunniffe, G.M., O'Brien, F.J., Partap, S., Levingstone, T.J., Stanton, K.T., Dickson, G.R. (2010) 'The synthesis and characterization of nanophase hydroxyapatite using a novel dispersant-aided precipitation method'. 95 (4):1142-1149. [Link] [DOI] | |
2010 | Matsiko, A., Levingstone, T.J., O'Brien, F.J., Gleeson, J.P. (2010) 'Addition of hyaluronic acid improves cellular infiltration and cartilage-specific extracellular matrix synthesis in a porous collagen scaffold'. 20 (SUPPL.2). [Link] | |
2010 | Levingstone, T.J., Dickson, G., O'Brien, F.J., Gleeson, J.P. (2010) 'A multi-layer collagen-based scaffold for osteochondral defect repair'. 20 (SUPPL.2). [Link] | |
2009 | García-Alonso D.;Levingstone T.;Parco M.;Stokes J. (2009) 'Plasma spray of free-standing components for bone tissue engineering'. Key Engineering Materials, 396-398 :695-698. [DOI] | |
2009 | Al-Munajjed, A.A., Plunkett, N.A., Gleeson, J.P., Weber, T., Jungreuthmayer, C., Levingstone, T., Hammer, J., O'Brien, F.J. (2009) 'Development of a biomimetic collagen-hydroxyapatite scaffold for bone tissue engineering using a SBF immersion technique'. 90 B (2):584-591. [Link] [DOI] |
Conference Publication
Online Article
Year | Publication | |
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2016 | Levingstone, T.J.; Gleeson, J.P.; O’Brien, F.J. (2016) Cartilage-repair technology helps injured thoroughbred return to showjumping. ELEA [Link] |
Review Articles
Year | Publication | |
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2019 | Levingstone T.;Herbaj S.;Dunne N. (2019) Calcium phosphate nanoparticles for therapeutic applications in bone regeneration. REV [DOI] | |
2020 | Levingstone, TJ;Herbaj, S;Redmond, J;McCarthy, HO;Dunne, NJ (2020) Calcium Phosphate Nanoparticles-Based Systems for RNAi Delivery: Applications in Bone Tissue Regeneration. BASEL: REV [DOI] |
Certain data included herein are derived from the © Web of Science (2023) of Clarivate. All rights reserved.
Honors and Awards
Outreach Activities
Media
Research Interests
Scaffolds, hydrogels and coatings for bone, cartilage and cardiovascular applications
Natural biomaterials for tissue regeneration, specifically collagen, hyaluronic acid and
chitosan
Advanced therapeutic strategies including cell and growth factor delivery and novel drug delivery systems
Advanced Biomaterial Manufacturing
Techniques including freeze-drying and 3D printing
Research Projects
Internal Collaborators
External Collaborators
Teaching Interests
Bioengineering, Biomaterials, Strength of Materials, Mechanics, Medical Devices, Rehabilitation Engineering