David Kinahan

Dr

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David Kinahan is an Assistant Professor in the School of Mechanical and Manufacturing Engineering since October 2018. David completed a BEng in Aeronautical Engineering (2003) and a PhD (2008) at University of Limerick (UL). His PhD focused on high-throughput droplet microfluidics for DNA analysis. In late 2007 David joined Stokes Bio Ltd, a spin-out from UL, as a Senior Engineer, and was later promoted to Engineering Manager leading a team of 10 engineers. In January 2012 David joined the Biomedical Diagnostics Institute  in DCU and since then has applied microfluidics to a wide range of application areas including human health (HIV diagnostics, CTC detection, CVD diagnostics, liver disease, early detection of bacterial meningitis) and point-of-use testing (plant pathogen detection, environmental monitoring etc). From January 2017 until October 2018 David was a Group Leader within Fraunhofer Project Center at Dublin City University (FPC@DCU).

Google Scholar Profile: https://scholar.google.com/citations?user=T3TNAB0AAAAJ&hl

Peer Reviewed Journal

Year Publication
2023 Rohit Mishra;Lourdes AN. Julius;Jack Condon;Patricija Pavelskopfa;Philip L. Early;Matthew Dorrian;Katarina Mrvova;Grace Henihan;Faith Mangwanya;Tanya Dreo;Jens Ducrée;Niall P. Macdonald;Cor Schoen;David J. Kinahan (2023) 'Plant pathogen detection on a lab-on-a-disc using solid-phase extraction and isothermal nucleic acid amplification enabled by digital pulse-actuated dissolvable film valves'. Analytica Chimica Acta, . [DOI]
2023 Kilcawley, N.A.;Voebel, T.C.;Early, P.L.;McArdle, N.A.;Renou, M.;Rio, J.;Saint-Martin, G.;Glynn, M.T.;Zontar, D.;Brecher, C.;Ducrée, J.;Kinahan, D.J. (2023) 'Dissolvable Film-Controlled Buoyancy Pumping and Aliquoting on a Lab-On-A-Disc'. Processes, 11 . [Link] [DOI]
2022 Mishra, R.;Alam, R.;McAuley, D.;Bharaj, T.;Chung, D.;Kinahan, D.J.;Nwankire, C.;Anderson, K.S.;Ducrée, J. (2022) 'Solvent selective membrane routing and microfluidic architecture towards centrifugal automation of customisable bead based immunoassays'. Sensors and Actuators: B. Chemical, 356 . [Link] [DOI]
2022 Chekotu, J.C., Goodall, R., Kinahan, D., Brabazon, D., (2022) 'Control of Ni-Ti phase structure, solid-state transformation temperatures and enthalpies via control of L-PBF process parameters'. MATERIALS & DESIGN, . [DOI]
2022 Regan, B.;Kinahan, D.;Daly, P.;O'Kennedy, R.;Collins, D. (2022) 'Design and fabrication of a low-cost wireless camera imaging system for centrifugal microfluidics'. Hardwarex, 11 . [Link] [DOI]
2022 Chekotu, JC;Kinahan, D;Goodall, R;Brabazon, D (2022) 'Influence of Structural Porosity and Martensite Evolution on Mechanical Characteristics of Nitinol via In-Silico Finite Element Approach'. Materials (Basel, Switzerland), 15 (15). [DOI]
2021 Uddin, R.;Kinahan, D.;Ducrée, J.;Boisen, A. (2021) 'Lab-on-a-disk extraction of PBMC and metered plasma from whole blood: An advanced event-triggered valving strategy'. Biomicrofluidics, 15 . [Link] [DOI]
2021 Kinahan, D.J.;Burger, R.;Lawlor, D.;Early, P.L.;Vembadi, A.;McArdle, N.A.;Kilcawley, N.A.;Glynn, M.T.;Ducrée, J. (2021) 'Centrifugally automated Solid-Phase Extraction of DNA by immiscible liquid valving and chemically powered centripetal pumping of peripherally stored reagents'. Biosensors and Bioelectronics: X, 9 . [Link] [DOI]
2021 Henderson BD;Kinahan DJ;Rio J;Mishra R;King D;Torres-Delgado SM;Mager D;Korvink JG;Ducrée J; (2021) 'Siphon-Controlled Automation on a Lab-on-a-Disc Using Event-Triggered Dissolvable Film Valves'. Biosensors, 11 (3). [DOI]
2020 Burger, R.;Kinahan, D.J.;Cayron, H.;Reis, N.;Fonseca, J.;Ducrée, J. (2020) 'Siphon-induced droplet break-off for enhanced mixing on a centrifugal platform'. Inventions, 5 . [Link] [DOI]
2018 Macdara T. Glynn and David J. Kinahan and Niamh A. McArdle and Jane L. Kendlin and Tr\'\iona M. O'Connell and Jens Ducrée (2018) 'A 3D-printed optical reader and wall projector for enumeration of CD4 cells in resource-limited point-of-care settings'. PLoS ONE, .
2018 Miyazaki C.;Kinahan D.;Mishra R.;Mangwanya F.;Kilcawley N.;Ferreira M.;Ducrée J. (2018) 'Label-free, spatially multiplexed SPR detection of immunoassays on a highly integrated centrifugal Lab-on-a-Disc platform'. Biosensors and Bioelectronics, 119 :86-93. [DOI]
2018 Delgado, Saraí M Torres,Kinahan, David J,Julius, Lourdes Albina Nirupa,Mallette, Adam,Ardila, David Sáenz,Mishra, Rohit,Miyazaki, Celina M,Korvink, Jan G,Ducrée, Jens,Mager, Dario (2018) 'Wirelessly powered and remotely controlled valve-array for highly multiplexed analytical assay automation on a centrifugal microfluidic platform'. 109 :214-223.
2017 Brennan, Des,Coughlan, Helena,Clancy, Eoin,Dimov, Nikolay,Barry, Thomas,Kinahan, David,Ducrée, Jens,Smith, Terry J,Galvin, Paul (2017) 'Development of an on-disc isothermal in vitro amplification and detection of bacterial RNA'. 239 :235-242.
2017 Celina M. Miyazaki and Rohit Mishra and David J. Kinahan and Marystela Ferreira and Jens Ducr\'ee (2017) 'Polyethylene imine/graphene oxide layer-by-layer surface functionalization for significantly improved limit of detection and binding kinetics for immunoassays on acrylate surfaces'. Colloids and Surfaces B: Biointerfaces, 158 :167-174. [DOI]
2016 David J. Kinahan and Philip L. Early and Abhishek Vembadi and Eoghan MacNamara and Niamh A. Kilcawley and Thomas Glennon and Dermot Diamond and Dermot Brabazon and Jens Ducr\'ee (2016) 'Xurography actuated valving for centrifugal flow control'. Lab on a Chip, 16 (18):3454-3459. [DOI]
2016 Saraí M. Torres Delgado and David J. Kinahan and Fralett Su\'arez Sandoval and Lourdes A.N. Julius and Niamh A. Kilcawley and Jens Ducr\'ee and Dario Mager (2016) 'Fully automated chemiluminescence detection using the electrified-Lab-on-a-Disc (eLoaD) platform'. Lab on a Chip, 16 (20):4002-4011. [DOI]
2016 Kinahan, David J,Kearney, Sinéad M,Kilcawley, Niamh A,Early, Philip L,Glynn, Macdara T,Ducrée, Jens (2016) 'Density-gradient mediated band extraction of leukocytes from whole blood using centrifugo-pneumatic siphon valving on centrifugal microfluidic discs'. 11 (5).
2016 Smith, Suzanne,Mager, Dario,Perebikovsky, Alexandra,Shamloo, Ehsan,Kinahan, David,Mishra, Rohit,Torres Delgado, Saraí M,Kido, Horacio,Saha, Satadal,Ducrée, Jens (2016) 'CD-based microfluidics for primary care in extreme point-of-care settings'. 7 (2).
2016 Kinahan, DJ;Renou, M;Kurzbuch, D;Kilcawley, NA;Bailey, E;Glynn, MT;McDonagh, C;Ducree, J (2016) 'Baking Powder Actuated Centrifugo-Pneumatic Valving for Automation of Multi-Step Bioassays'. Micromachines, 7 . [DOI]
2015 Macdara Glynn, Charles Nwankire, Kate Lemass, David J Kinahan, Jens Ducrée (2015) 'Cluster size distribution of cancer cells in blood using stopped-flow centrifugation along scale-matched gaps of a radially inclined rail'. Microsystems & Nanoengineering, .
2015 David Kinahan and Sin\'ead Kearney and Olivier Faneuil and Macdara Glynn and Jens Ducr\'ee (2015) 'Paper imbibition for timing of multi-step liquid handling protocols on event-triggered centrifugal microfluidic lab-on-a-disc platforms'. 5 (3):1818-1826. [DOI]
2014 Glynn, Macdara,Kirby, Daniel,Chung, Danielle,Kinahan, David J,Kijanka, Gregor,Ducrée, Jens (2014) 'Centrifugo-magnetophoretic purification of CD4+ cells from whole blood toward future HIV/AIDS point-of-care applications'. 19 (3):285-296.
2014 David J. Kinahan and Sin\'ead M. Kearney and Nikolay Dimov and Macdara Glynn and Jens Ducr\'ee (2014) 'Event-triggered logical flow control for comprehensive process integration of multi-step assays on centrifugal microfluidic platforms'. 14 (13):2249-2258. [DOI]
2014 Macdara Glynn, David Kinahan and Jens Ducrée (2014) 'Rapid, low-cost and instrument-free CD4+ cell counting for HIV diagnostics in resource-poor settings'. Lab on a Chip, 14 :2844-2851. [DOI]
2013 Glynn, Macdara T,Kinahan, David J,Ducrée, Jens (2013) 'CD4 counting technologies for HIV therapy monitoring in resource-poor settings–state-of-the-art and emerging microtechnologies'. 13 (14):2731-2748.
2009 David Kinahan , Tara Dalton , Mark Davies (2009) 'Measurement of substrate thermal resistance using DNA denaturation temperature'. International Journal of Thermal Sciences, 49 :333-339.
2009 David J. Kinahan , Tara M. Dalton , Mark RD. Davies (2009) 'Effect of substrate thermal resistance on space-domain microchannel'. 11 :747-754.
2012 Robert Burger and Daniel Kirby and Macdara Glynn and Charles Nwankire and Mary O'Sullivan and Jonathan Siegrist and David Kinahan and Gerson Aguirre and Gregor Kijanka and Robert A. Gorkin III and Jens Ducr\'ee (2012) 'Centrifugal microfluidics for cell analysis'. 16 (3-4):409-414. [DOI]

Review Articles

Year Publication
2021 Zaresharif, Mahshid;Ravelet, Florent;Kinahan, David J.;Delaure, Yan M. C. (2021) Cavitation control using passive flow control techniques. REV [DOI]

Book Chapter

Year Publication
2016 Henderson B.;Kinahan D.;Ducrée J. (2016) 'The centrifugal microfluidic: Lab-on-a-disc platform' In: Microfluidics for Biologists: Fundamentals and Applications. [DOI]
2016 Mohammadi, Mahdi and Kinahan, David J and Ducr\'ee, Jens (2016) 'Lumped-Element Modeling for Rapid Design and Simulation of Digital Centrifugal Microfluidic Systems' In: Lab-on-a-Chip: Fabrication and Application. xx : InTech.
2015 Nwankire, Charles E and Kinahan, David J and Ducr{\'e}e, Jens (2015) 'Centrifugal Flow Control' In: Encyclopedia of Microfluidics and Nanofluidics. New York : Springer.
2015 Kinahan, David J and Glynn, Macdara T and Ducr{\'e}e, Jens (2015) 'Microfluidic Cell Enumeration for Biomedical Diagnostics' In: Encyclopedia of Microfluidics and Nanofluidics. New York : Spring.
2014 Mishra, R and Gaughran, J and Kinahan, D and Ducr{\'e}e, J (2014) 'Functional Membranes for Enhanced Rotational Flow Control on Centrifugal Microfluidic Platforms' In: Reference Module in Materials Science and Materials Engineering. Elsevier : Elsevier.

Conference Publication

Year Publication
2019 Sriram Thoppe Rajendran, Khorshid Kamguyan, David Kinahan, En-Te Hwu, Line Hagner Nielsen, Kinga Zór, and Anja Boisen (2019) 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences,, Basel, SWITZERLAND Artificial Gut-on-a-Disc Platform to Evaluate PH Sensitive Coating for Oral Drug Delivery Devices
2019 Eimear Higgins, Cian Merne, Patrick Wogan, David Collins, Sarai M. Torres-Delgado, Dario Mager and David J. Kinahan (2019) 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences,, Basel, SWITZERLAND Differential Second Degree of Freedom Centrifugal Microfluidics
2018 Berger M.;Müller T.;Voebel T.;Baum C.;Glennon T.;Mishra R.;Kinahan D.;King D.;Ducrée J.;Brecher C. (2018) Progress in Biomedical Optics and Imaging - Proceedings of SPIE Automated assembly of microfluidic lab-on-A-disc [DOI]
2018 Kinahan D.;Delgado S.;Julius L.;Mallette A.;Saenz-Ardila D.;Mishra R.;Miyazaki C.;Korvink J.;Mager D.;Ducree J. (2018) Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) Wireless closed-loop control of centrifugo-pneumatic valving towards large-scale microfluidic process integration [DOI]
2018 Brennan D.;Coughla H.;Clancy E.;Dimov N.;Barry T.;Kinahan D.;Ducree J.;Smith T.;Galvin P. (2018) 2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings Development of a system for on-disc isothermal in vitro amplification and detection of bacterial RNA [DOI]
2017 Celina Miyazaki and David J. Kinahan and Rohit Mishra and Marystela Ferreira and Jens Ducr\'ee (2017) Proceedings of the 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences ($\mu$TAS 2017), October 22--26, Savannah, Georgia, USA . In: Abraham Lee and Don DeVoe eds. Immunosensing by centrifugally automated surface-plasmon resonance detection based on a smartphone camera
2016 David J. Kinahan and Danielle Chung and Jens Ducr\'ee (2016) Proceedings of the 11$^\rm th$ Rapid Methods Europe on Food, Feed and Water Analysis (RME 2016) held in Amsterdam, The Netherlands, 7 -- 9 November An automated centrifugal microfluidic platform for on-site applications
2016 David J. Kinahan and Faith Mangwanya and Robert Garvey and Danielle W. Y. Chung and Artur Lipinski and Lourdes A. N. Julius and Damien King and Rohit Mishra and Mehdi Mohammadi and May Al-Ofi and Celina Miyazaki and Jens Ducr\'ee (2016) Proceedings of the 27th Micromechanics and Microsystems Europe Workshop (MME 2016) in Cork, Ireland, August 28-30 Automation of silica bead-based nucleic acid extraction on a centrifugal Lab-on-a-Disc platform
2016 Sara\'\i M. Torres Delgado and David J. Kinahan and Niamh A. Kilcawley and Lourdes A. N. Julius and Brian Henderson and Jan G. Korvink and Jens Ducr\'ee and Dario Mager (2016) Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences ($\mu$TAS 2016), October 9--13, The Convention Centre Dublin, Ireland . In: Nicole Pamme and Jens Ducr\'ee eds. A fully automated wirelessly powered centrifugal platform towards a sample-to-answer chemiluminescent ELISA assay for CVD detection
2016 Mahdi Mohammadi and David J. Kinahan and Jens Ducr\'ee (2016) Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences ($\mu$TAS 2016), October 9--13, The Convention Centre Dublin, Ireland . In: Nicole Pamme and Jens Ducr\'ee eds. Lumped element simulation of a highly integrated bioanalytical centrifugal processing unit (\lq\lq BioCPU)
2016 David J. Kinahan and Kate McConville and Brian Henderson and Margaret McCaul and Eoghan McNamara and Dermot Diamond and Jens Ducr\'ee (2016) Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences ($\mu$TAS 2016), October 9--13, The Convention Centre Dublin, Ireland . In: Nicole Pamme and Jens Ducr\'ee eds. Digital pulse actuated flow control on a centrifugal disc towards multiparameter water quality monitoring
2016 Brian Henderson and David J. Kinahan and Jeanne Rio and Rohit Mishra and Damien King and Sarai Torres-Delgado and Dario Mager and Jan Korvink and Jens Ducr\'ee (2016) Proceedings of the 26th Anniversary World Congress on Biosensors (Biosensors 2016), Swedish Exhibition and Congress Centre, Gothenburg, Sweden, May 25--27 . In: Anthony P. F. Turner eds. Timing of a centrifugally automated, multi-step chemiluminescent CRP assay towards a point-of-care for early-stage detection of cardiovascular disease
2015 Macdara T. Glynn and Jane L. Kendlin and David J. Kinahan and Jens Ducr\'ee (2015) Proceedings of the 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences ($\mu$TAS 2015), October 25--29, Gyeongju City, Korea . In: Je-Kyun Park eds. A 3D-printed optical reader for cost-efficient enumeration of CD4 cells for point-of-care diagnostics of HIV in resource-poor settings
2015 Glynn M.;Kendlin J.;Kinahan D.;Ducrée J. (2015) MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences A 3D-printed optical reader for cost-efficient enumeration of cd4 cells for point-of-care diagnostics of HIV in resource-poor settings
2015 Glynn, M;Nwankire, C;Kinahan, D;Ducree, J (2015) 2015 28TH IEEE INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS 2015) CLUSTER SIZING OF CANCER CELLS BY RAIL-BASED SERIAL GAP FILTRATION IN STOPPED-FLOW, CONTINUOUS SEDIMENTATION MODE
2015 Mishra R.;Alam R.;Kinahan D.;Anderson K.;Ducree J. (2015) Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) Lipophilic-membrane based routing for centrifugal automation of heterogeneous immunoassays [DOI]
2015 Rohit Mishra and Rizwan Alam and David J. Kinahan and Karen Anderson and Jens Ducr\'ee (2015) Proceedings of the 28th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2015), January 18 -- 22, Estoril, Portugal . In: J\urgen Brugger and Wouter van der Wijngaart eds. Lipophilic-membrane based routing for centrifugal automation of heterogeneous immunoassays
2015 David J. Kinahan and Robert Burger and Abhishek Vembadi and Niamh A. Kilcawley and Daryl Lawlor and Macdara T. Glynn and Jens Ducr\'ee (2015) Proceedings of the 28th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2015), January 18 -- 22, Estoril, Portugal . In: J\urgen Brugger and Wouter van der Wijngaart eds. Baking-powder driven centripetal pumping controlled by event-triggering of functional liquids
2015 Glynn M.;Nwankire C.;Kinahan D.;Ducree J. (2015) Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) Cluster sizing of cancer cells by rail-based serial gap filtration in stopped-flow, continuous sedimentation mode [DOI]

Other Publication

Year Publication
2021 Kinahan, D.J.;Mager, D.;Vereshchagina, E.;Miyazaki, C.M. (2021) Special issue on “advances in microfluidics technology for diagnostics and detection”. [Link] [DOI]
Certain data included herein are derived from the © Web of Science (2023) of Clarivate. All rights reserved.

Professional Associations

Association Function From / To
Engineers Ireland Member -

Patents

Patent Number Title Inventor Granted
EP2994232B1 Rotatable microfluidic device with dissolvable release valve and control valve David J Kinahan et al 02/05/2018
US11344888B2 Fluidic device for aliquoting and combinatorial mixing of liquids David Kinahan
US10513729B2 Biological detection system and method of use David J Kinahan

Research Projects

Title Role Description Start date End date
Proof-of-Concept PCR Thermocycler with Integrated Microfluidic Liquid Handling DCU PI 01/03/2020 31/05/2021
Arraying of Liquids for Medium-Throughput Screening Applications (MxN Chip) DCU PI 01/05/2017 31/07/2017
Innovation Eco-system to Accelerate the Industrial Uptake of Advanced Surface Nano-Technologies DCU PI 01/04/2020 31/03/2024
Low-cost Automation of Molecular Diagnostic Assays (LAMDA) PI 01/06/2020 31/05/2021

Current Postgraduate Students

Student Name Degree Supervision
Chekotu ,Josiah Cherian PhD Supervisor
Zaresharif ,Mahshid PhD-track Supervisor
Cholkar ,Abhijit Suhas PhD-track Supervisor
Mc Mullan ,Tara MEng Supervisor
Saeed ,Muhammad Mubashar PhD-track Supervisor

Modules Coordinated

Term Title Subject
2022 Fundamentals of Control MM353
2022 Product Design, Development & Value Analysis MM523
2022 Manufacturing Processes 1 MM252